Mariko Rosebank is a loving housewife with a great husband and son. One day, while with her son at the airport to see her husband off to a business trip, a terrorist attack destroys the whole terminal, leaving Mariko without a son and husband. With a scar that looks like a rose flower as the only injury, she uses the tragedy to form a civilian counter-terrorism organisation, known as CAT (Counter Attack Terrorism), and devote her life to dealing with all sorts of global terrorist threats and attacks.
6 months after the murder of her father, Ryuko Matoi arrives at Honnouji Academy, a high school ruled with an iron fist by Satsuki Kiryuin, leader of the student council. Upon failing to beat Satsuki for answers, Ryuko stumbles upon a sentient sailor uniform. Naming him Senketsu, Ryuko sets out to beat the Elite Four, liberate the school from its iron grip and find out once and for all the truth behind her father's murder.
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